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Case reports and epidemiology studies in female subjects on colchicine therapy have not established a clear relationship between colchicine use and female infertility.

It is high in corosolic (colosolic) acid, a triterpenoid compound, which is used in many drugs for diabetes.

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You will also pay attention to other well known causes including poor diet (caloric or protein restriction), major illness or surgeries, major psychological stress, significant weight loss, chronic iron deficiency, thyroid disorders, and childbirth.

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If tophi are present, if radiography shows evidence of damage, if attacks are frequent or disabling, or if there are relative contraindications to the drugs that would be needed to treat acute attacks, then hypouricemic therapy should be strongly considered to reduce the burden of urate in the body, resorb tophi, and ultimately reduce the frequency of gout flares.

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These “heroes of alternative medicine” stories fit into their anti-NHS agenda, as they are further proof of how conventional medicine, typified by the NHS, lets people down.

For instance, the FDA points out that Colcrys' orphan exclusivity applies only to the FMF indication.

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COLCRYS is a prescription medication generally used to treat acute flairs in patients with gout.

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Colcrys (colchicine, USP) tablets are indicated in adults and children 4 years or older for treatment of familial Mediterranean fever (FMF).

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Dietary causes account for about 12% of gout, and include a strong association with the consumption of alcohol, -sweetened drinks, meat and seafood.

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